Conference Program

Program incl. confirmed invited speakers

Monday, 27 August 2018
Modelling Biological Barriers:
non-animal models for facilitating clinical translation; epi-/ endothelial barriers: lung, skin, GI, BBB; non-cellular barriers: mucus and surfactant; modelling diseased barriers: infection and inflammation; microfluidics and bioprinting

Heike Walles/ TERM, University Hospital Würzburg:
Complex human  co-culture tissue models and their application in drug development
Josué Sznitman/ Israel Institute of Technology:  Advanced airway-on-chip platforms: bridging in vitro and in vivo pulmonary interfaces
Katharina Ribbek/ MIT: Microbial Interactions and Transport in the Mucus Barrier
Pankaj Karande/ Rensselaer: Engineering Vascularized Human Skin using 3D Printing
Olivier Guenat and Nina Hobi/ University of Bern: Organs-on-chip models of the air-blood barrier
Maximiliano Gutierrez/ Francis Crick Institute: Crossing barriers to improve tuberculosis treatment
Maike Windbergs/ University of Frankfurt: The human skin in heathy and diseased state – in vitro models and imaging approaches
Hamid Ghandehari/ University of Utah: Biological Fate and Toxicity of Dendritic and Silica Nanoconstructs

Tuesday, 28 August 2018
Drug Delivery: nanomedicine; gene delivery; functional polymers; intelligent systems; innovative carriers and materials; how to move/ delivery without diffusion and convection; immunotherapy, immonological barriers and vaccine delivery
Tejal Desai/ UCSF: Nanostructured Materials for Therapeutic Delivery and Immunomodulation
Patrick Stayton/ University of Washington: Engineering Intracellular Drug Therapies
André Nel/ UCLA: Use of a Nano-enabled Dual Drug Delivery Platform for Cancer Immunotherapy
Peer Fischer/ MPG:  Directed Transport with Nanopropellers
David Brayden/ University College Dublin:
Progress using nanoparticulates and permeation enhancers to deliver oral peptides
Eva Roblegg/ University of Graz: Drug Delivery Strategies for Treatment of Oral Diseases
Jesus Perez-Gil/ University of Madrid: Surfing the Respiratory Surface for Smart Drug Delivery
Thomas Crouzier: Modulating the barrier properties of mucus

Wednesday, 29 August 2018 (morning session)
Extracellular Vesicles: mammalian EVs: exosomes, microvesicles, cell-cell communication, drug targeting, EV-therapeutics, minimally invasive diagnostics; bacterial EV: outer membrane vesicles, bacterial interaction, host cell modulation, OMV vaccines
David Carter/ Oxford Brooks University: Extracellular vesicles as communicators of cellular stress
David Whitworth/ Abersystwyth University: Antimicrobial OMVs from bacterial predators: physiology, cargo and mechanism
Raymond Schiffelers/ Utrecht University: Extracellular vesicles versus liposomes
Mario Gimona/ Paracelsus Medizinische Privatuniversität: Manufacturing and regulatory aspects for EVs to reach the clinic

Wednesday, 29 August 2018 (afternoon session)
Advanced nanomedicine to overcome biological barriers (in cooperation with European ITN NABBA)
Gert Storm/ Utrecht University: Targeted drug delivery: are our expectations justified?
Maria-José Alonso/ University of Santiago de Compostela: Formulation of macromolecules using nanotechnology
Patrick Couvreur/ CNRS: Nanomedicines for the treatment of severe diseases
Jean-Christophe Leroux/ ETH; Delivery of a liposomal O6-methylguanine-DANN methyltransferase inactivator to glioblastoma via ultrasound-supported blood-brain barrier opening

Slots for contributed presentations are provided in each session. The selection will be based on the review of the 1-page abstract by the Programme Chairs. A poster exhibition with the contributions of the participants will be present during the whole conference. Instructions for abstract submission will be published in due time.